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Formed in 2004 by sisters Alexia and Anissa Rodriguez, Arizona's Eyes Set To Kill set out to create their own take on the screamo genre. To fill out the lineup, vocalist and guitarist Alexia Rodriguez and bassist Anissa Rodriguez recruited vocalist and synth player Brandon Anderson, guitarist Greg Kerwin, and drummer Caleb Clifton. The group combines the driving emotion of Thursday and Thrice with technical hardcore reminiscent of Walls of Jericho and Poison the Well. The result is a fusion of the heavy and the melodic, with Alexia Rodriguez's vocals soaring high over the thunder of chugging guitars and Anderson's tortured screaming, creating a sound that expands the boundaries of the genre, moving away from the screamo blueprint.